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KMID : 0360220020430020357
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Journal of the Korean Ophthalmological Society
2002 Volume.43 No. 2 p.357 ~ p.362
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MALT (mucosa associated lymphoid tissue) type Lymphoma of the Ocular Adnexa
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Cho Young-Joon
Yim Jin-Ho
Park Keun-Sung
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Abstract
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Purpose: To report MALT (mucosa associated lymphoid tissue) type lymphoma in ocular adnexa.
Methods: This retrospective study included 11 patients (13 cases) of MALT type lymphoma between Agust 1995 and July 2000. We identified 11 lymphoma cases with MALT characteristics by conventioal examination and immunohistochemical
staining.
Twelve cases were treated with partial excision and radiotherapy, one case with partial excision and chemotherapy.
Results: The patients consisted of 4 females and 7 males with an age range of 29~88 (average 48) years old. Mean follow up period was 24.8 (6~60) months following treatment. Eleven patients had ocular adnexal involvement at presentation; 7
eyes
in conjunctiva, 5 eyes in orbit and one in eyelid. All cases represented extranodal marginal zone B-cell lymphoma by REAL classificaiton. Control of lymphomas was achieved in all but 4 cases which developed recurrence after irradiation and
chemotherapy,
and were salvaged with further radiotherapy. Complications such as cataract, radiation retinopathy, ptosis and alopecia developed later in 4 eyes.
Conclusion: Surgical excision and radiotherapy seemed to be effective for the treatment of pimary ocular adnexal MALT lymphoma. Long-term follow up should be warranted.
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KEYWORD
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Excision and radiotherapy, Immunohistochemical stain, MALT lymphoma,
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